Confronting the Opioid Crisis: A School-based Education Outreach Program will enable a cohort of high school students to access biomedical and health information, learn about the prevalence of this epidemic in their neighborhoods, communities and county, the health consequences, and steps needed to reduce its impact especially on school students. Program will address the current efforts being used to save lives and resources available to them if they need treatment. Offered as a partnership and collaborative effort, the program is an integrated, in-class, student-centered, experiential, and technology-driven youth empowerment project offered to a cohort of students once every week during the 2019-2020 school year. Using MedlinePlus and other NIH resources, the overarching goal is to create health literate public high school students able to navigate the internet to obtain, comprehend, and understand basic health knowledge about prescription 103, the dangers of 103 abuse, misuse, and practice informed decision-making about their health. Students will create a one-minute video to share with their peers as part of this education awareness campaign. Both qualitative and quantitative data will be captured to establish program outcomes and also feedback on program implementation.