Dr. Nadine Burke Harris was already known as a crusading physician delivering targeted care to vulnerable children. But it was Diego—a boy who had stopped growing after a sexual assault—who galvanized her journey to uncover the connections between toxic stress and lifelong illnesses. Burke Harris’s resulting research revealed just how deeply our bodies can be imprinted by ACEs—adverse childhood experiences like abuse, neglect, parental addiction, mental illness, and divorce. Childhood adversity changes our biological systems and lasts a lifetime.The Deepest Well: Healing the Long-Term Effects of Childhood Trauma and Adversity aids our understanding of how ACEs are encoded in our body and offers hope by sharing important interventions for preventing lifelong illness for both those we love and for future generations.