The National Black Nurses Annual conference aims to provide attendees with essential knowledge to tackle multifaceted issues in nursing, healthcare, and health equity. Its objectives include exploring the impact of bioinformatics, biotechnology, AI, and novel innovations on healthcare and nursing, while addressing health disparities. It also emphasizes the importance of community partnerships in enhancing the built environment and population health, and highlights emerging care models for better chronic condition management and treatment adherence. Additionally, the conference will cover effective management and leadership strategies for nursing leaders, identify trends affecting health equity and public health justice, and discuss the significance of including diverse racial, ethnic, and disadvantaged populations in clinical research to ensure comprehensive health outcomes.