Archive for the ‘Data’ Category
Wednesday, March 29th, 2017
“Untitled” by Darren Coleshill is licensed under CC0/span>.
From winter into spring, the transition is beautiful. Trees are full of leaves and flowers are in full bloom. In Texas, the bluebonnets grace our highways. The sun is out, shining brightly. Suddenly, some of us start wheezing, coughing, and sneezing.
According to the National Institute of Environmental Health Sciences (NIEHS), allergens in the environment can trigger seasonal allergies and asthma. Asthma is an inflammatory disease of the lung and is now the most common chronic disorder in childhood. The prevalence has increased over the years. According to CDC Vital Signs 1 in 12 people have asthma in the United States. Oxygen absorption in the lungs is a crucial function of the body. With asthma, the airway becomes inflamed, swollen, and narrow. Less air is able to get to the lung tissue. Some describe feeling as if an elephant is sitting on their chest.
The US Department of Housing and Urban Development conducted an extensive survey, known as the National Survey of Lead Hazards and Allergens in Housing. The results were published in the Journal of Allergy and Clinical Immunology. It found that 46% of homes had dust mite allergens high enough to produce allergic reactions and one quarter of the homes had allergen levels high enough to trigger asthma symptoms in susceptible individuals. Nearly two-thirds of American homes have cockroach allergens.
What can we do? See the NIEHS Fact Sheet for some simple steps for decreasing indoor allergens. See the NIEHS and the NHLBI for more information.
Like NNLM SCR on Facebook and like us on Twitter.
Tuesday, February 7th, 2017
“Scale” by mojzagrebinfo is licensed under CC0.
Making fun of a person’s weight, often called “fat shaming,” is probably not going to motivate a person to lose weight. In fact, it will most likely raise their risk of heart disease and other health problems.
Rebecca Pearl, assistant professor of psychology at the University of Pennsylvania’s Perelman School of Medicine and study leader, said that the more self-blame and devaluation a person feels when stigmatized, the more likely they are to have health issues.
Previous research has linked weight stigmatization with weight gain and emotional stress but this study found weight stigmatization can go much deeper.
The study looked at 159 obese adults and found out how much they blamed and devalued themselves for their weight. They also looked at how many of them had been diagnosed with metabolic syndrome, a cluster of risk factors that are linked with higher risks of heart disease, type 2 diabetes and more health problems.
The study found that those who felt the most devaluation and self-blame were three times more likely to have metabolic syndrome than the those with the lowest.
Dr. Rebecca Puhl, deputy director at the University of Connecticut Center for Food Policy & Obesity who co-wrote a commentary that accompanied the study, said to try to avoid self-blame as well as try to avoid blaming friends and family for struggling with weight.
To read more about the study, please visit “The Shame of ‘Fat Shaming.’”
Follow NN/LM SCR on Twitter and like us on Facebook.
Wednesday, January 27th, 2016
The National Institutes of Health will fund a set of genome sequencing and analysis centers whose research will focus on understanding the genomic bases of common and rare human diseases. The National Human Genome Research Institute (NHGRI), part of NIH, January 14, 2016 launched the Centers for Common Disease Genomics (CCDG), which will use genome sequencing to explore the genomic contributions to common diseases such as heart disease, diabetes, stroke and autism. NHGRI also announced the next phase of a complementary program, the Centers for Mendelian Genomics (CMG), which will continue investigating the genomic underpinnings of rare, typically inherited diseases, such as cystic fibrosis and muscular dystrophy. “Advances in DNA sequencing are creating tremendous new opportunities for exploring how the genome plays a role in human disease,” said NHGRI Director Eric Green, M.D., Ph.D. “Our continued focus on both rare and common diseases promises to reveal important aspects about the genomic architecture of a wide range of human disorders.”CCDG researchers plan to examine a select group of disorders in order to develop approaches for using genome sequencing to study common disease more broadly. By sequencing an expected 150,000 to 200,000 genomes of individuals with these diseases, the CCDG program aims to improve understanding of how genomic differences among people influence disease risk and to develop models for future studies of common disease.
NHGRI is one of the 27 institutes and centers at the National Institutes of Health. The NHGRI Extramural Research Program supports grants for research and training and career development at sites nationwide. Additional information about NHGRI can be found at www.genome.gov.
Tuesday, December 22nd, 2015
Adapted from: FDA Voice Blog
The U.S. Food and Drug Administration on Tuesday December 15, 2015 has launched the beta version of precisionFDA, its a new collaborative platform designed to foster innovation and to develop the science behind a method of “reading” DNA also known as Next-Generation Sequencing (or NGS). Next Generation Sequencing allows scientists to compile data on a person’s exact order or sequence of DNA. The precisionFDA includes more than 20 public and private sector participants including National Institutes of Health (NIH), Centers for Disease Control and Prevention, National Institute of Standards and Technology (NIST) and more. Dr. Francis Collins, NIH’s Director stated on https://precision.fda.gov/ that “PrecisionFDA, is a bold and innovative step towards advancing the regulatory science for precision medicine”.
PrecisionFDA allows users to access tools such as “Genome in the Bottle“https://www.genomeweb.com/sequencing-technology/nist-genome-bottle-release-first-reference-material-assessing-genome, a reference sample of DNA for validating genome sequences developed by NIST. These results can be compared with results of previously validated references, and shared with other users, who can track changes and obtain immediate feedback from precisionFDA users. In FDA Voice http://blogs.fda.gov/fdavoice/, Tasha A. Kass-Hout, MD, chief informatics officer at the FDA wrote, “His hope is to grow the community of platform participants and improve the usability of precisionFDA in the coming months and years by placing the code for the precisionFDA portal on the world’s largest open source software repository, GitHub”.
Friday, December 18th, 2015
Adapted from NLM:
The National Library of Medicine, in partnership with Boston University School of Medicine has announced the creation of the Health Literacy Tool Shed. The online database allows users to obtain information of more than 100 health literacy research instruments and compare them to others.
Robert A. Logan Ph.D., senior staff, National Library of Medicine explains, “The new Health Literacy Tool Shed helps users choose the right instrument for their research or practice. It also helps researchers assess core issues, such as the impact of health literacy on health outcomes and health care utilization.”
Tuesday, December 8th, 2015
Adapted from the NLM Tech Bull. 2015 Nov-Dec;(407):b9.
To automatically receive the latest news and announcements regarding major changes and updates to NCBI resources and tools please see the subscribe page.
NCBI Webinar: “Accessing 1000 Genomes Project Data” on December 17, 2015
December 17, 2015, NCBI staff will demonstrate how to access 1000 Genomes data through SRA, dbVar, SNP and BioProject, as well as through tracks on annotated human sequences in the graphical sequence viewer and Variation Viewer. Attendees will also learn how to display, search, and download individual and genotype level data through the dedicated 1000 Genomes Browser that allows searching by chromosomal position, gene names and other genome markers.
Date and Time: December 17, 2015 11:00a.m. – 12:00p.m. MT; 12:00p.m.-1:00p.m. CST
Registration URL: https://attendee.gotowebinar.com/register/5168155820927556866
After the live presentation, the Webinar will be uploaded to the NCBI YouTube channel. Any related materials will be accessible on the Webinars and Courses page; you can also find information about future Webinars on this page.
Tuesday, December 1st, 2015
National Human Genome Research Institute (NHGRI)
Tuesday, December 1st, 2015
Big Data to Knowledge (BD2K) updates from NIH and NSF
The National Science Foundation recently posted an article on advances in big data and the management of chronic diseases.
The National Institutes of Health has released new Data Science Funding Opportunities: The new NIH Common Fund program Molecular Transducers of Physical Activity has released funding opportunities including one for a bioinformatics center. Applications are due March 18, 2016.
Article of Interest: How to hijack a Journal.
Tuesday, November 3rd, 2015
The National Institutes of Health (NIH) Office of the Associate Director for Data Science (ADDS) announces a collaboration with the Wellcome Trust (WT) and the Howard Hughes Medical Institute (HHMI) to launch the “Open Science Prize” (the “Challenge”) to encourage and support the prototyping and development of services, tools and/or platforms that enable open content—including publications, datasets, code and other research outputs—to be discovered, accessed and re-used in ways that will advance research, spark innovation, and generate new societal benefits. The Challenge is necessary to accelerate the field of “open” biomedical research beyond what current funding mechanisms can achieve. For the NIH, this Challenge is being launched under the America COMPETES Reauthorization Act of 2010.
See more at https://datascience.nih.gov/bd2k/announcements/research
Monday, October 26th, 2015
The Journal of eScience Librarianship (JESLIB) is an open access, peer-reviewed journal that advances the theory and practice of librarianship with a special focus on services related to data-driven research in the physical, biological, social, and medical sciences, including public health.
JESLIB explores the many roles of librarians in supporting eScience and welcomes articles by contributors from all areas of the globe related to education, outreach, collaborations, policy, tools, and best practices. The journal includes peer-reviewed articles discussing topics such as research data management, librarians embedded on research teams, data services, data curation, and data sharing and re-use. Submissions covering both theoretical and practical applications are welcomed.
JESLIB does not charge subscription, submission, or author fees and authors retain ownership of the copyright for their content.
Edited by Elaine Martin, Director of the NN/LM New England Region, JESLIB is a product of the eScholarship@UMMS digital repository and supports the National Institute of Health’s big data missions, including the BD2K (Big Data to Knowledge) initiative.