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NLM’s DailyMed Web Site Redesigned With New Features and Improved Usability!

DailyMed web site

On September 18 the National Library of Medicine launched a newly redesigned DailyMed web site. DailyMed provides trustworthy information about marketed drugs in the United States, and is the official provider of Food and Drug Administration (FDA) label information. The web site provides a standard, comprehensive, up-to-date, look-up and download resource of medication content and labeling found in medication package inserts. Since 2005, when DailyMed was first launched, its usage has increased significantly.

Based on the needs and feedback received from the public, NLM began redesigning the DailyMed web site in 2013. The new site is a responsive design which is now easily accessible on all types of devices, adjusting and optimizing automatically for smart phones to large screen desktop displays. Based on the size of the screen, content will relocate, images will resize, the layout will change, and even the navigation will adjust, to deliver an exceptional user experience no matter what device is being used to view the site.

In addition to responsive design, the following new features are available:

  • Enhanced Search Results to include displaying of NDC Codes, Pill Images, and Package Label Images on the search result page. The information will help users easily identify the drug label. The thumbnail images of drugs, magnification feature, accordions, etc. provide a more user friendly experience.
  • Improved user interface by displaying an accordion-style data presentation, so users don’t have to scroll through the entire label.
  • Simplified page navigation and added definitions & tooltips for industry-specific phrases.
  • A dedicated News page and Article & Presentation Page for users to easily access DailyMed and NLM/FDA drug-related news.

NLM Releases Rare Footage of President Franklin Roosevelt Speaking at NIH

On October 31, 1940, just days before President Franklin D. Roosevelt would be elected to an unprecedented third term as President of the United States, he traveled to Bethesda to dedicate the National Cancer Institute and the new campus of what was then the National Institute of Health (NIH), before it would eventually become known in plural form, National Institutes of Health, as multiple units were established over subsequent years. That late October afternoon, Roosevelt stood on the steps of the new main NIH building, ready to address a crowd of 3,000 people. Still relevant today, in a variety of contexts, are the subjects he discussed: the need for preparedness in light of war and for research into deadly diseases, recent improvements in public health and health care, and hope that the research conducted at NIH would lead to new cures for and even the prevention of disease.

The National Library of Medicine is making the film of Roosevelt’s speech publicly available online for the first time, nearly 74 years after the President made his speech. Sound recordings, transcripts, and photographs of this event have been publicly available for many years. Research suggests, however, that this rare film footage has not been seen publicly since its recording and may no longer exist anywhere else. The recording does not appear to have been professionally produced, since the camera is unsteady in places, a hand sweeps across the lens, and the filming starts and stops, though it isn’t known whether this is a result of the original filming or of later editing. The film is publicly available via the NLM’s Digital Collections archive of over 10,000 biomedical books and videos, and its YouTube site. Read more about this historically significant film footage on the NLM blog, Circulating Now: From the Historical Collections of the World’s Largest Biomedical Library.

TOXMAP and Native American Populations

Although the National Library of Medicine’s TOXMAP resource is not specifically designed for any one particular group, the TRI and Superfund Programs can be of interest to specific populations such as Native Americans, by helping to find sources of chemical releases and contamination in locations of interest to them.

In the beta version of TOXMAP, click on the “Zoom to Location” icon, enter “reservation” or “rancheria” into the “Address or Place” search box, and then click “Zoom to.” In TOXMAP classic, click on “Zoom to a Place,” enter “reservation” or “rancheria” into the “other place name” search box, and then click “Submit.” You can also overlay US Census data by race: “American Indian and Alaskan Native” (1990) or “One Race: American Indian and Alaska Native” and “Two or More Races Including American Indian and Alaska Native” (2000). For more information, visit the TOXMAP and Native American Populations webpage.

MeSH Browser Now Updated More Frequently

Beginning on September 4, 2014, the MeSH Browser is being updated each business day. The MeSH XML and ASCII format files for Supplementary Concept Records (SCRs) will be available on this same Monday through Friday schedule starting the week of September 15, 2014. Prior to this change, the MeSH Browser and MeSH XML and ASCII files for SCRs were updated and made available once per week.

This new update schedule releases new and edited SCRs, mostly for chemicals and drugs, in a more timely way for use by both indexers and searchers. Descriptors and qualifiers are changed only on an annual basis.

2015 Medical Subject Headings (MeSH) Now Available!

MeSH Vocabulary Changes for 2015 is now available! Lists of new descriptors, changed descriptors, deleted descriptors, and new descriptors by tree subcategory are available on the NLM website. For more information about MeSH use and structure, as well as recent updates and availability of data, visit the updated Introduction to MeSH – 2015 webpage.

Note: The default year in the MeSH Browser remains 2014 MeSH for now, but the alternate link provides access to 2015 MeSH. The MeSH Section will continue to provide access via the MeSH Browser for two years of the vocabulary; the current year and an alternate year. Sometime in November or December, the default year will change to 2015 MeSH and the alternate link will provide access to the 2014 MeSH.

Population Health Added to Special Queries

The NLM PubMed Special Queries page includes a link to a new MEDLINE/PubMed Population Health search. A definition for population health is “the health outcomes of a group of individuals, including the distribution of such outcomes within the group. The field of population health includes health outcomes, patterns of health determinants, and policies and interventions that link these to differences between groups of people.” 1

The Population Health Special Query is a PubMed search of relevant MeSH headings and text words combined strategically to retrieve PubMed citations. MeSH headings were selected with the assistance of members of the Institute of Medicine Board on Population Health and Public Health.

1 Kindig D, Stoddart G. What is population health? Am J Public Health. 2003 Mar;93(3):380-3. PubMed PMID: 12604476.

PubChem Turns Ten!

PubChem logoSeptember 16, 2004 is a special day in the history of PubChem. It marks the beginning of PubChem as an on-line resource! Now fast forward ten years. PubChem provides information daily to many tens of thousands of users. Despite the passage of time, PubChem’s primary mission remains the same: providing comprehensive information on the biological activities of chemical substances.

Providing chemical information to researchers in the biomedical science community is a key part of PubChem’s purpose. Over the years, PubChem introduced and incrementally developed several interfaces, each with its own distinct purpose and set of use cases. Primary to these is the Entrez search interface, where PubChem is organized as three distinct databases: Substance, Compound, and BioAssay. Substance provides substance descriptions (accession number: SID), Compound provides the unique small-molecule chemical content of Substance (accession number: CID), and BioAssay provides biological experiment results for substances (accession number: AID). Each of these databases has an advanced search interface and contain numerous indexes and filters, which can be combined to construct elaborate queries. Additional interfaces exist to search and analyze information in PubChem, including the ability to analyze bioactivity information, download chemical and assay data, search by chemical structure or protein sequence, navigate using integrated classifications, visualize chemical 3-D information, and more.

PubChem continues to evolve the way it provides on-line content. External search engines (like Google, Bing, and others) are now a key way in which researchers locate data. In addition, programmatic interfaces now account for a significant portion of PubChem’s overall usage (+50%). Key programmatic interfaces to PubChem include Entrez Utilities and PUG/REST.

NLM Medical Text Indexer Plays Role in International Challenge

For the second year in a row, the National Library of Medicine (NLM) Medical Text Indexer was used as one of the baselines for the international BioASQ Challenge. The Medical Text Indexer (MTI) combines the expertise of indexers working at NLM with natural language processing technology to curate the biomedical literature with Medical Subject Headings (MeSH®) more efficiently and consistently. BioASQ is a series of challenges on biomedical semantic indexing and question answering with the aim of advancing the state of the art accessibility for researchers and clinicians to biomedical text. The MTI indexing results are providing one of the baselines used in the “large-scale online biomedical semantic indexing” part of the challenge, which is designed to parallel the human indexing currently being done at NLM. The NLM Medical Text Indexer is a product of the close collaboration between the NLM Index Section and the Lister Hill National Center for Biomedical Communications, an Intramural Research Division of the National Library of Medicine.

The BioASQ Challenge evaluation of approaches to biomedical semantic indexing provided a continuous assessment of the indexing suggestions that are automatically generated by the MTI system used in support of the MEDLINE® indexing process at the NLM. The benefits of participating in this community-wide evaluation for MTI were two-fold: firstly, MTI was rigorously compared to systems developed by a world-wide community of researchers and industrial teams all performing the same task; and secondly, the free exchange of the methods and ideas allowed the MTI team to incorporate the best practices explored by the participating teams. Incorporating some of these approaches into the MTI workflow in 2013-2014 improved the accuracy of MTI indexing suggestions by 4.5%.

NCBI RefSeq Release 67 Available on FTP

The full RefSeq release 67 is now available on the NCBI FTP site with over 61 million records describing 45,166,402 proteins; 8,163,775 RNAs; and sequences from 41,913 different NCBI TaxIDs. More details about the RefSeq release 67 are included in the release statistics and release notes. In addition, reports indicating the accessions included in the release and the files installed are available.

To subscribe to the ncbi-announce mailing list, visit http://www.ncbi.nlm.nih.gov/mailman/listinfo/ncbi-announce.

National Library of Medicine Resource Update: Environmental Health Student Portal

The National Library of Medicine Environmental Health Student Portal has added Mercury and Your Health, an animation about the uses of mercury and how exposure can impact human health. The 16-minute video introduces children to mercury and its basic properties, discusses mercury exposure routes, outlines health impacts of mercury, describes mercury containing products, discusses mercury contamination in the environment, outlines the proper disposal of mercury containing products, discusses bioaccumulation and mercury contamination of fish, and describes additional sources that children could use to find credible health information on mercury.

The Environmental Health Student Portal connects middle school students and science teachers with free, reliable, and engaging environmental health education resources. The Student Portal offers a diverse array of engaging educational materials such as videos, games and activities, lesson plans, experiments and projects, fun challenges, as well as additional resources for further reading. Mercury is one of the chemicals covered in this resource.