The HIV-1, human interaction database has been updated and is now on an improved page. The improved interface includes help documentation and supports structured queries against Gene, as well as browsing, filtering and downloading the protein and replication interaction data sets. The most recent data release (June 2014) includes 12,785 HIV-1, human protein-protein interactions for 3,142 human genes and 1,316 replication interactions for 1,250 human genes. The HIV-1, human interactions project, collates published reports of two types of interactions – HIV-1, human protein interactions, and human gene knock-downs that affect virus replication which are reported as “replication interactions.”
Archive for the ‘Public Health’ Category
On September 18 the National Library of Medicine launched a newly redesigned DailyMed web site. DailyMed provides trustworthy information about marketed drugs in the United States, and is the official provider of Food and Drug Administration (FDA) label information. The web site provides a standard, comprehensive, up-to-date, look-up and download resource of medication content and labeling found in medication package inserts. Since 2005, when DailyMed was first launched, its usage has increased significantly.
Based on the needs and feedback received from the public, NLM began redesigning the DailyMed web site in 2013. The new site is a responsive design which is now easily accessible on all types of devices, adjusting and optimizing automatically for smart phones to large screen desktop displays. Based on the size of the screen, content will relocate, images will resize, the layout will change, and even the navigation will adjust, to deliver an exceptional user experience no matter what device is being used to view the site.
In addition to responsive design, the following new features are available:
- Enhanced Search Results to include displaying of NDC Codes, Pill Images, and Package Label Images on the search result page. The information will help users easily identify the drug label. The thumbnail images of drugs, magnification feature, accordions, etc. provide a more user friendly experience.
- Improved user interface by displaying an accordion-style data presentation, so users don’t have to scroll through the entire label.
- Simplified page navigation and added definitions & tooltips for industry-specific phrases.
- A dedicated News page and Article & Presentation Page for users to easily access DailyMed and NLM/FDA drug-related news.
On October 31, 1940, just days before President Franklin D. Roosevelt would be elected to an unprecedented third term as President of the United States, he traveled to Bethesda to dedicate the National Cancer Institute and the new campus of what was then the National Institute of Health (NIH), before it would eventually become known in plural form, National Institutes of Health, as multiple units were established over subsequent years. That late October afternoon, Roosevelt stood on the steps of the new main NIH building, ready to address a crowd of 3,000 people. Still relevant today, in a variety of contexts, are the subjects he discussed: the need for preparedness in light of war and for research into deadly diseases, recent improvements in public health and health care, and hope that the research conducted at NIH would lead to new cures for and even the prevention of disease.
The National Library of Medicine is making the film of Roosevelt’s speech publicly available online for the first time, nearly 74 years after the President made his speech. Sound recordings, transcripts, and photographs of this event have been publicly available for many years. Research suggests, however, that this rare film footage has not been seen publicly since its recording and may no longer exist anywhere else. The recording does not appear to have been professionally produced, since the camera is unsteady in places, a hand sweeps across the lens, and the filming starts and stops, though it isn’t known whether this is a result of the original filming or of later editing. The film is publicly available via the NLM’s Digital Collections archive of over 10,000 biomedical books and videos, and its YouTube site. Read more about this historically significant film footage on the NLM blog, Circulating Now: From the Historical Collections of the World’s Largest Biomedical Library.
Although the National Library of Medicine’s TOXMAP resource is not specifically designed for any one particular group, the TRI and Superfund Programs can be of interest to specific populations such as Native Americans, by helping to find sources of chemical releases and contamination in locations of interest to them.
In the beta version of TOXMAP, click on the “Zoom to Location” icon, enter “reservation” or “rancheria” into the “Address or Place” search box, and then click “Zoom to.” In TOXMAP classic, click on “Zoom to a Place,” enter “reservation” or “rancheria” into the “other place name” search box, and then click “Submit.” You can also overlay US Census data by race: “American Indian and Alaskan Native” (1990) or “One Race: American Indian and Alaska Native” and “Two or More Races Including American Indian and Alaska Native” (2000). For more information, visit the TOXMAP and Native American Populations webpage.
The NLM PubMed Special Queries page includes a link to a new MEDLINE/PubMed Population Health search. A definition for population health is “the health outcomes of a group of individuals, including the distribution of such outcomes within the group. The field of population health includes health outcomes, patterns of health determinants, and policies and interventions that link these to differences between groups of people.” 1
The Population Health Special Query is a PubMed search of relevant MeSH headings and text words combined strategically to retrieve PubMed citations. MeSH headings were selected with the assistance of members of the Institute of Medicine Board on Population Health and Public Health.
1 Kindig D, Stoddart G. What is population health? Am J Public Health. 2003 Mar;93(3):380-3. PubMed PMID: 12604476.
The National Library of Medicine Environmental Health Student Portal has added Mercury and Your Health, an animation about the uses of mercury and how exposure can impact human health. The 16-minute video introduces children to mercury and its basic properties, discusses mercury exposure routes, outlines health impacts of mercury, describes mercury containing products, discusses mercury contamination in the environment, outlines the proper disposal of mercury containing products, discusses bioaccumulation and mercury contamination of fish, and describes additional sources that children could use to find credible health information on mercury.
The Environmental Health Student Portal connects middle school students and science teachers with free, reliable, and engaging environmental health education resources. The Student Portal offers a diverse array of engaging educational materials such as videos, games and activities, lesson plans, experiments and projects, fun challenges, as well as additional resources for further reading. Mercury is one of the chemicals covered in this resource.
The National Library of Medicine (NLM) Household Products Database (HPD) now contains over 14,000 products. The latest update includes a new product category “commercial/institutional.” Product manufacturers of the more than 300 products in this category use various descriptions, including professional grade, professional use, hospital grade, and more. Users can locate products using the new “commercial/institutional” link under “Browse by Category” on the HPD homepage or by entering the category/description terms (e.g. commercial, institutional, professional, hospital) as a Quick Search.
The Household Products Database links over 14,000 consumer brands to health effects from Material Safety Data Sheets (MSDS) provided by manufacturers, and allows scientists and consumers to research products based on chemical ingredients. The database is designed to help answer the following typical questions:
- What are the chemical ingredients and their percentage in specific brands?
- Which products contain specific chemical ingredients?
- Who manufactures a specific brand? How do I contact this manufacturer?
- What are the acute and chronic effects of chemical ingredients in a specific brand?
- What other information is available about chemicals in the toxicology-related databases of the National Library of Medicine?
Information in the Household Products Database comes from a variety of publicly available sources, including brand-specific labels and Material Safety Data Sheets when available from manufacturers and manufacturers’ web sites.
The National Library of Medicine has announced a new Value Set Authority Center (VSAC) tutorial, Updating Value Sets. The nine-minute tutorial is available as a link from the UMLS Video Learning Resources page, the NLM Distance Education Resources page, and is posted at the NLM YouTube site. Additional tutorials designed to assist users with VSAC and VSAC authoring tools are in development. NLM encourages comments about the tutorial and suggestions for further topics, which may be sent to NLM Customer Service.
The NLM Value Set Authority Center is developed by NLM in collaboration with Office of the National Coordinator for Health IT (ONC) and the Centers for Medicare & Medicaid Services (CMS) to provide searchable access to value sets that are used to define concepts used in clinical quality measures, and to support effective health information exchange and many other biomedical informatics applications and programs. Since October 2013, VSAC also offers the Authoring Tool that allows users to author value sets.
The National Library of Medicine (NLM) has updated Haz-Map with 497 new agents. It now covers 10,133 biological and chemical agents. Haz-Map is an occupational health database designed for health and safety professionals and for consumers seeking information about the health effects of exposure to chemicals and biologicals at work. Haz-Map links jobs and hazardous tasks with occupational diseases and their symptoms. More information is available from the Haz-Map Fact Sheet.
University of Maryland, Baltimore, Health Sciences and Human Services Library, Announces Release of Student Health Advocates Redefining Empowerment Curriculum
The Health Sciences and Human Services Library, University of Maryland, Baltimore, has announced the release of the Student Health Advocates Redefining Empowerment (SHARE) Curriculum, developed as the result of a three-year Health Information Resource Grant to Reduce Health Disparities (G08LM0011079) from the National Library of Medicine. The grant aimed to empower high school students as community health advocates, improve health in Baltimore neighborhoods, and develop a replicable student health advocacy program. The entire curriculum consists of six modules. Each module can be used independently as well. The modules are:
- Overview of Health Disparities
- Quality Health Information
- Taking Charge of Your Health
- Smart Food Choices
- Crafting and Delivering the Message
- Promoting Health and Wellness in Your Community
These modules were developed after working with two cohorts of students from Vivien T. Thomas Medical Arts Academy in Baltimore. In addition to detailed lesson plans, each class has assignments and handouts and is aligned with national standards. Supplemental activities are also provided. In order to build a community around the curriculum, a blog is available to share ideas and suggestions and discuss the curriculum. For more information, please contact Project SHARE.