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Archive for the ‘NLM Resources’ Category

Thai Clinical Trials Registry Added to the MEDLINE Databank Sources

NLM will be including the databank name for the Thai Clinical Trials Registry (TCTR) starting with citations to articles published in 2014. TCTR is a World Health Organization (WHO) primary clinical trial registry. The MEDLINE Databank Sources webpage has been updated to include this new listing.

Other clinical trial databank sources that appear in the Secondary Source ID [SI] element in the PubMed MEDLINE display include:

  • ClinicalTrials.gov Database (NIH/NLM)
  • Australian New Zealand Clinical Trials Registry
  • Chinese Clinical Trials Registry
  • Clinical Research Information Service, Republic of Korea
  • Clinical Trials Registry – India
  • German Clinical Trials Register
  • EU Clinical Trials Register
  • Iranian Registry of Clinical Trials
  • International Standard Randomized Controlled Trial Number (ISRCTN.org) Register
  • Japan Primary Registries Network
  • The Netherlands National Trial Register
  • Pan African Clinical Trial Register
  • Brazilian Clinical Trials Registry
  • Cuban Public Registry of Clinical Trials
  • Sri Lanka Clinical Trials Registry

AIDSinfo Releases Free Drug App for iOS and Android Devices!

AIDSinfo HIV/AIDS Drug Database screenshotAIDSinfo has announced the release of the AIDSinfo HIV/AIDS Drug Database app. Using data from the AIDSinfo Drug Database, the drug app provides information on more than 100 HIV-related approved and investigational drugs. The information, offered in English and Spanish, is tailored to meet the needs of both health care providers and consumers. The app is designed to automatically refresh when the user is connected to a wireless or cellular data network. The auto update feature eliminates the need to manually update the app to view the most current drug information. In addition, the app works offline, ensuring that health care providers and consumers can access vital drug information anywhere, even in health care facilities that may not have an Internet connection.

Health care providers surveyed on the AIDSinfo website indicated that access to Food and Drug Administration (FDA) labels for HIV-related drugs would be a useful feature of a drug app. Thus FDA drug labels pulled from DailyMed are integrated into the app in an easy-to-navigate format. This feature, coupled with the auto update feature, makes it easy for health care providers to quickly find the latest drug information when seeing patients. In addition, information from the FDA labels is condensed in easy-to-understand summaries in English and Spanish for consumers. The app also includes information on HIV-related investigational drugs for both health care providers and consumers.

Available for both iOS and Android devices, users can personalize the free AIDSinfo Drug App to suit their needs:

  • Receive notifications when content is updated.
  • Bookmark frequently referenced drugs for easy access at any time.
  • Add personal notes to any drug.
  • Select from a menu of alarms to set pill reminders for any drug.

AIDSinfo also has the AIDSinfo Glossary of HIV/AIDS-Related Terms app, available for both iOS and Android devices, which includes English and Spanish definitions of more than 700 HIV/AIDS-related terms.

NLM Resource Update: Radiation Emergency Medical Management (REMM) Website

The following updates and changes were announced in November, 2014, for the National Library of Medicine’s Radiation Emergency Medical Management (REMM) website:

  1. Initial Actions for Responders after Nuclear Detonation: First Receivers: Emergency Department Staff and First Responders: Emergency Medical Service Staff.
  2. Multimedia: many new videos and graphics including 13 new teaching videos from DOE / Transportation Emergency Preparedness Program (TEPP) available on the REMM web site and REMM YouTube channel. Also links to various new CDC teaching materials, such as Videos: Radiation Basics Made Simple.
  3. Protective Actions and Protective Action Guides: page redone with re-organized information and tables. EPA PAG Manual Interim Guidance included.
  4. Burn Triage and Treatment: Thermal Injuries includes links to new references for managing burns in mass casualty incidents with austere conditions.
  5. Legal Advisors for Medical Response to Mass Casualty Incident: new references and 2 new sections including assessment of state and local laws regarding management of persons during radiation incidents including legal authority to decontaminate and quarantine (CDC and partners).
  6. Nuclear Detonation: Weapons, Improvised Nuclear Devices Key References entire list re-organized and updated, including Medical Issues: Planning and Response Practical Guidance and updated Blast injury references.
  7. Dictionary of Radiation Terms: 2 new key references, NCRP Glossary of Radiation Terms and NCRP Acronyms List.
  8. Biodosimetry References updated and re-organized.
  9. Software Tools for Radiation Incident Response includes additional applications listed for biodosimetry, managing incidents, and recording radiation levels.
  10. Incident Command System and Hospital (Emergency) Incident Command System page re-organized with links to HICS, Fifth edition, 2014, expanded to meet the needs of all hospitals, regardless of their size, location or patient care capabilities.
  11. Mental Health Professionals now includes updated references on Psychological First Aid.

New NLM Subject Guide for Genetic/Genomics Information!

The National Library of Medicine has released a new Genetics/Genomics Information subject guide as the latest update in its subject guide series. These guides, based on most frequently asked questions, are starting points for health professionals, researchers, librarians, students, and others. The guide is designed to help you find introductory materials relating to Genetics and Genomics, such as basic features of the human genome and its organization into chromosomes. It is not comprehensive in scope or coverage, particularly for specific genetic conditions or new and improved technologies. The guide provides links to bioinformatics gateways for more genetic information, and points primarily to free electronic items, or records for materials that may be available via your library. The guide has a section of links for professional education, and a section suggesting how to use PubMed to search for citations to published research journal literature for more information about a particular disease or condition. Other published guides in the NLM series include:

NLM will develop more subject guides as needed. NLM welcomes comments, questions, and suggestions about all of the guides.

December 2014 Issue of NIH News in Health Now Available!

Illustration of friends relaxing by a fireplace.Check out the December issue of NIH News in Health, the monthly newsletter bringing you practical health news and tips based on the latest NIH research. In this issue:

  • Feeling Stressed? Stress Relief Might Help Your Health
    Winter holidays—do they fill you with joy or with worries about gift-giving and family gatherings? Do summer vacations leave you relaxed or fretful over travel and money? If you’re feeling stressed out over supposedly fun things, it might be time to reassess. Take a few moments to learn how stress affects your health and what you can do about it.
  • Detecting Rare Disease-Causing Glitches
    For people with suspected rare genetic conditions, getting an accurate diagnosis can be difficult and frustrating. A new study suggests that a fast, powerful technique called whole-exome sequencing can help doctors pinpoint the causes of many hard-to-diagnose genetic conditions.
  • A Priceless Gift: Your Family Health History
    Conditions such as cancer, heart disease, and diabetes often run in families. Tracing the illnesses of your parents, grandparents, and other blood relatives can help your health care practitioner predict your risk for specific disorders. It could suggest vital screening tests and treatments before any disease is evident. That’s why it’s so important to discuss your family’s health history.
  • Featured Website: Go4Life
    This interactive site helps adults, ages 50 and older, to fit more physical activity into their days. A science-based exercise guide, videos, success stories, motivational tips, and free materials can help you get ready, start exercising, and keep moving.

NIH News in Health is available online in both HTML and PDF formats. Print copies are available free of charge for offices, clinics, community centers, and libraries within the U.S. Visit the NIH News in Health Facebook page to suggest topics you’d like to see covered, or share what you find helpful about the newsletter!

Structured Abstracts in MEDLINE: Newly Identified and Mapped Labels Available

The National Library of Medicine (NLM) has updated its list of structured abstract labels. This updated list, along with the NLM-assigned broader category mappings, can be downloaded for free from the Structured Abstracts resource page which also provides NLM guidelines and other background information to assist licensees or researchers.

The Updated Label List and NLM Category Mappings file contains 2,799 labels: 2,454 labels (from the 2013 Label List) and 345 new labels. Each label has a map to one of five corresponding broader NLM Categories (i.e., BACKGROUND, OBJECTIVE, METHODS, RESULTS, or CONCLUSIONS) and an indication of whether the label is classed as an “Ending Label” concept. The 345 new label entries have a timestamp of “|20141113″. This file does not contain labels that map to UNASSIGNED as an NLM Category (see explanation). A grand total of 4,514 citations in PubMed (whether in process, MEDLINE, or PubMed-not-MEDLINE status) were revised to reflect the new labels effective on or about November 13, 2014.

Read more about Structured Abstracts in MEDLINE/PubMed.

PMC Citation Exporter Feature Now Available!

PMC (PubMed Central) is happy to announce the addition of a citation exporter feature. This feature makes it easy to retrieve either styled citations that you can copy/paste into your manuscripts, or to download them into a format compatible with your bibliographic reference manager software.

When viewing a search results page, each result summary will now include a “Citation” link. When, clicked, this will open a pop-up window that you can use to easily copy/paste citations formatted in one of three popular styles: AMA (American Medical Association), MLA (Modern Library Association, or APA (American Psychological Association). In addition, the box has links at the bottom that can be used to download the citation information in one of three machine-readable formats, which most bibliographic reference management software can import. The same citation box can also be invoked from an individual article, either in classic view (with the “Citation” link among the list of formats) or the PubReader view, by clicking on the citation information just below the article title in the banner.

Citation Exporter Feature screenshot

These human-readable styled citations, and machine-readable formats, will be available through a public API. Further details will be provided in another announcement, on the pmc-utils-announce mailing list. Please subscribe to that list if you are interested in updates.

NLM Resource Update: ChemIDplus Drawing Feature

The National Library of Medicine’s (NLM) ChemIDplus resource is a dictionary of over 400,000 chemicals (names, synonyms, and structures). It includes links to NLM and to other databases and resources, including ones to federal, state and international agencies. You can draw a chemical structure and search for similar substances using the ChemIDplus Advanced search interface. This feature also performs similarity and substructure searches. A four-minute tutorial is available for using the drawing feature of ChemIDplus. The ChemIDplus Lite interface is designed for simple searching on name or registry number.

HHS and NIH Request Public Comments on Steps to Enhance Transparency of Clinical Trial Results

The Department of Health and Human Services (HHS) and the National Institutes of Health (NIH) are releasing for public comment two proposals to increase the transparency of clinical trials via information submitted to ClinicalTrials.gov, a publicly accessible database operated by the National Library of Medicine. The first is a Notice of Proposed Rulemaking (NPRM) that describes proposed regulations for registering and submitting summary results of certain clinical trials to ClinicalTrials.gov in compliance with Title VIII of the Food and Drug Administration Amendments Act of 2007 (FDAAA). A major proposed change from current requirements is the expansion of the scope of clinical trials required to submit summary results to include trials of unapproved, unlicensed, and uncleared products. The second proposal is a draft NIH policy that would extend the similar registration and reporting requirements to all clinical trials funded by NIH, regardless of whether they are subject to FDAAA. Both proposals aim to improve public access to information about specified clinical trials, information that is not necessarily available from other public sources. The proposals are not intended to affect the design or conduct of clinical trials or define what type of data should be collected during a clinical trial. Rather, they aim to ensure that information about clinical trials and their results are made publicly available via ClinicalTrials.gov. A summary of the proposed changes is available from the NIH.

The public may comment on any aspect of the NPRM or proposed NIH Policy. Written comments on the NPRM should be submitted to docket number NIH-2011-0003. Commenters are asked to indicate the specific section of the NPRM to which each comment refers. Written comments on the proposed NIH Policy should be submitted electronically to the Office of Clinical Research and Bioethics Policy, Office of Science Policy, NIH, via email; mail at 6705 Rockledge Drive, Suite 750, Bethesda, MD 20892; or by fax at 301-496-9839, by March 23, 2015. All comments will be considered in preparing the final rule and final NIH Policy.

Turn the Pages of a Rare Book on Mongolian Astrology from the NLM Collections

The National Library of Medicine announces the release of a new Turning the Pages virtual book on its Web site, via iPad App, and in kiosks onsite at the NLM. The new project features selections from a colorfully illustrated 19th-century manuscript from Mongolia on astrology and divination following Mongolian and Tibetan Buddhist traditions.

Basics of Mongolian AstrologyThis Turning the Pages project includes a selection of 15 images from the over 40 pages in the Mongolian Book of Astrology and Divination, along with a curator’s descriptive text, putting many divine figures and astronomical charts into context for a modern Western audience. For instance, many of the astrological factors calculable among the charts corresponded to different organs of the body or life events such as birth, old age, illness, and death. The ultimate goal was keeping one’s life in balance with the cosmos, using the calculations in this manuscript to choose an auspicious time to begin a new project, conceive a child, receive a treatment, or even remove the corpse of a loved one from one’s home.

Launched at the NLM in 2001, Turning the Pages represents an ongoing collaboration between research engineers at the Lister Hill National Center for Biomedical Communications and curators and historians at the NLM’s History of Medicine Division, to help make the NLM’s rare and unique history of medicine collections widely available to the public. To date, Turning the Pages has offered the public access to a wide range of early printed books and manuscripts that span centuries, cover topics from surgery and anatomy to botany and horse veterinary medicine, and originate from places as diverse as Iran, Japan, Egypt, Italy, and now Mongolia. The NLM’s copy of Mongolian Book of Astrology and Divination is just one item from its Buddhist Mongolian and Tibetan materials relating to health and disease. The Library holds one of the world’s largest collections of early books relating to East Asian health and medicine.