The National Library of Medicine’s (NLM) ChemIDplus resource is a dictionary of over 400,000 chemicals (names, synonyms, and structures). It includes links to NLM and to other databases and resources, including ones to federal, state and international agencies. You can draw a chemical structure and search for similar substances using the ChemIDplus Advanced search interface. This feature also performs similarity and substructure searches. A four-minute tutorial is available for using the drawing feature of ChemIDplus. The ChemIDplus Lite interface is designed for simple searching on name or registry number.
Archive for the ‘NLM Resources’ Category
The Department of Health and Human Services (HHS) and the National Institutes of Health (NIH) are releasing for public comment two proposals to increase the transparency of clinical trials via information submitted to ClinicalTrials.gov, a publicly accessible database operated by the National Library of Medicine. The first is a Notice of Proposed Rulemaking (NPRM) that describes proposed regulations for registering and submitting summary results of certain clinical trials to ClinicalTrials.gov in compliance with Title VIII of the Food and Drug Administration Amendments Act of 2007 (FDAAA). A major proposed change from current requirements is the expansion of the scope of clinical trials required to submit summary results to include trials of unapproved, unlicensed, and uncleared products. The second proposal is a draft NIH policy that would extend the similar registration and reporting requirements to all clinical trials funded by NIH, regardless of whether they are subject to FDAAA. Both proposals aim to improve public access to information about specified clinical trials, information that is not necessarily available from other public sources. The proposals are not intended to affect the design or conduct of clinical trials or define what type of data should be collected during a clinical trial. Rather, they aim to ensure that information about clinical trials and their results are made publicly available via ClinicalTrials.gov. A summary of the proposed changes is available from the NIH.
The public may comment on any aspect of the NPRM or proposed NIH Policy. Written comments on the NPRM should be submitted to docket number NIH-2011-0003. Commenters are asked to indicate the specific section of the NPRM to which each comment refers. Written comments on the proposed NIH Policy should be submitted electronically to the Office of Clinical Research and Bioethics Policy, Office of Science Policy, NIH, via email; mail at 6705 Rockledge Drive, Suite 750, Bethesda, MD 20892; or by fax at 301-496-9839, by February 19, 2015. All comments will be considered in preparing the final rule and final NIH Policy.
The National Library of Medicine announces the release of a new Turning the Pages virtual book on its Web site, via iPad App, and in kiosks onsite at the NLM. The new project features selections from a colorfully illustrated 19th-century manuscript from Mongolia on astrology and divination following Mongolian and Tibetan Buddhist traditions.
This Turning the Pages project includes a selection of 15 images from the over 40 pages in the Mongolian Book of Astrology and Divination, along with a curator’s descriptive text, putting many divine figures and astronomical charts into context for a modern Western audience. For instance, many of the astrological factors calculable among the charts corresponded to different organs of the body or life events such as birth, old age, illness, and death. The ultimate goal was keeping one’s life in balance with the cosmos, using the calculations in this manuscript to choose an auspicious time to begin a new project, conceive a child, receive a treatment, or even remove the corpse of a loved one from one’s home.
Launched at the NLM in 2001, Turning the Pages represents an ongoing collaboration between research engineers at the Lister Hill National Center for Biomedical Communications and curators and historians at the NLM’s History of Medicine Division, to help make the NLM’s rare and unique history of medicine collections widely available to the public. To date, Turning the Pages has offered the public access to a wide range of early printed books and manuscripts that span centuries, cover topics from surgery and anatomy to botany and horse veterinary medicine, and originate from places as diverse as Iran, Japan, Egypt, Italy, and now Mongolia. The NLM’s copy of Mongolian Book of Astrology and Divination is just one item from its Buddhist Mongolian and Tibetan materials relating to health and disease. The Library holds one of the world’s largest collections of early books relating to East Asian health and medicine.
The National Library of Medicine (NLM) has released a new version of Chemical Hazards Emergency Medical Management (CHEMM). CHEMM is a Web-based resource that can be downloaded in advance to Windows and Mac computers to ensure availability during an event if the Internet is not accessible. CHEMM’s content is also integrated into the NLM Wireless Information System for Emergency Responders (WISER), which is Web-based and downloadable to Windows computers. CHEMM’s content is also available in WISER’s iOS and Android apps. The new CHEMM content will be incorporated into the next release of WISER.
New or updated content in CHEMM includes:
- Updated and enhanced content on Decontamination Procedures, Discovering the Event, and Training and Education
- An NIH CounterACT program funded database with information on twenty-two medical countermeasures (including efficacy, relevant publications, research in progress, FDA and other global regulatory status information)
- Content for how emergency responders can recognize and handle events dealing with toxic gases generated by the combinations of consumer products or common household chemicals
- A workshop report describing toxic chemical syndromes, or toxidromes, that lays the foundation for a consistent lexicon for use in CHEMM and for other uses that, if adopted widely, will improve response to chemical mass exposure incidents
- A toxidromes outreach plan whose goal is to raise widespread awareness and encourage use of the toxidromes throughout the stakeholder community, and
- An evaluation and validation plan for CHEMM’s Intelligent Syndromes Tool (CHEMM-IST) that, once completed, will move CHEMM-IST from its current state as a prototype to a product ready for use in an operational response environment.
For more information see the “What’s New on CHEMM?” section of CHEMM.
The National Library of Medicine (NLM) provides online environmental health student resources for students in grades 1-12. The information and data in the following resources are free and vetted by science professionals. The resources can be used by science educators in their classrooms, in after school programs, in home school programs, and by students for their academic research assignments.
- Environmental Health Student Portal (Grades 6-8): Provides middle school students and educators with information on common environmental health topics such as water pollution, climate change, air pollution, and chemicals.
- Toxicology Tutorials (Grades 9-12+): Teach basic toxicology principles; written at the introductory college student level.
- Household Products Database (Grades 6-12+): Learn about the potential health effects of chemicals in common household products ranging from personal hygiene products to landscape care products.
- ToxTown (Grades 6-12+): Interactive guide to commonly encountered toxic substances. Includes classroom materials. Also available in Spanish.
- TOXMAP (Grades 9-12+): Uses maps of the United States to visually explore Superfund and Toxic Release Inventory (TRI) sites and data from the EPA. Includes classroom materials.
- Native Voices Exhibition Lesson Plans & Activities (Grades 6-12): Familiarize students with Native American, Alaska Native and Native Hawaiian healthcare by using the NLM Native Voices exhibition Web site content materials.
- ToxMystery (Grades 1-5): Teaches elementary school students about toxic substances in the home. Game format; includes lesson plans and activities. Also available in Spanish.
The National Library of Medicine’s Refugee Health Information Network (RHIN) resource was a national collaborative partnership with the principal focus of creating and making available a database of quality multilingual/multicultural, public health resources to professionals providing care to resettled refugees and asylees. In October, 2014, NLM’s Specialized Information Services (SIS) broadened the scope of RHIN by rebranding it HealthReach. This was done to better meet the needs of the diverse non-English and English as a second language speaking audiences. HealthReach continues to recognize the importance of providing refugee and asylee specific information while expanding the information provided to meet the needs of most immigrant populations. Over the next several months new resources will be added to the web site. There is also a new Twitter feed, @NLM_HealthReach. There isn’t much change between the old RHIN and the new HealthReach; this was intentional to help with the continuity of service through the transition.
The National Library of Medicine has just announced the release of new versions of the MedlinePlus Mobile sites in English and Spanish. Like the original versions of the mobile sites, the redesigned sites are optimized for mobile phones and tablets. Unlike the original mobile sites that contained only a subset of the information available on MedlinePlus, the new sites have all of the content found on MedlinePlus and MedlinePlus en español! They also have an improved design for easier use on mobile devices. Illustrations of the new sites are available in the NLM Technical Bulletin.
The key features of the redesigned mobile sites are:
- Access to all the content available on MedlinePlus and MedlinePlus en español
- Improved navigation using “Menu” and “Search” options to access search and major areas of the sites
- Enhanced page navigation with the ability to open and close sections within pages
- Updated look and feel with a refreshed design
This new version of MedlinePlus Mobile is the first step in redesigning MedlinePlus and MedlinePlus en español to behave responsively. Responsively designed Web sites automatically change their layouts to fit the screen of the device on which they are viewed, whether that is a desktop monitor or a mobile touchscreen. In 2015, the MedlinePlus team will release a fully responsive version of MedlinePlus to provide a consistent user experience from the desktop, tablet, or phone. This will obviate the need for a separate mobile site. Users will then have one destination for MedlinePlus when using any device. Until then, try out this first offering of MedlinePlus’s responsive design on your smartphone! Feel free to send feedback and comments about the new site via the “Contact Us” link that appears on every page.
The National Library of Medicine (NLM) has launched a Web collecting initiative to capture and preserve selected born-digital content documenting the 2014 Ebola outbreak. This initiative is a part of its previously-announced Web content collecting effort, which is guided by the NLM Collection Development Manual and other strategic collecting efforts. Initiated on October 1, 2014, selected content related to the current Ebola outbreak includes Web sites and social media from Government and non-government organizations, journalists, healthcare workers, and scientists in the United States and around the world, with an aim to collect and preserve a diversity of perspectives on this unfolding health crisis.
The content is part of the NLM’s broader Web collection on “Global Health Events.” The NLM will continue to develop, review, describe, and add content to the collection, as it also expands its overall capacity to collect Web content. With this initiative NLM has taken a major new step in its mission to collect pertinent health care information of today for the benefit of research in the future. Increasingly, that information is found on the Web, which is a rapidly changing environment where valuable and interesting materials can surface and then quickly disappear!
The National Library of Medicine (NLM) is accepting applications for its 2015-16 Associate Fellowship program, a one-year training program designed for recent MLS graduates and early-career librarians. All U.S. and Canadian citizens who will have earned a MLS or equivalent degree in library/information science from an ALA-accredited school by August 2015 are eligible to apply. Priority is given to U.S. citizens. Applications and additional information are available on the NLM web site. The application deadline is February 5, 2015. Between 4 and 7 fellows will be selected for the program.
In the first half of the fellowship year, a formal curriculum offers exposure to library operations, research and development, intramural and extramural research, development and lifecycle of NLM’s web-based products and services, and the extensive outreach and education program reaching consumers, special populations, health professionals and librarians. In the second half of the year, Associate Fellows have the opportunity to choose projects based on real-world problems proposed by library divisions, and work with librarians and library staff over a 6-7 month period. Successful projects have led to peer-reviewed publications, and to services that have become a regular part of library operations.
The September through August program also offers professional development and an introduction to the wider world of health sciences librarianship that may include:
- Supported attendance at national professional conferences, often including the Medical Library Association’s annual meeting, the American Medical Informatics Association annual meeting and others
- Additional brown bags, seminars, field trips and learning opportunities available on the National Institutes of Health campus
- Opportunities to meet and interact with senior management at the National Library of Medicine
- Experienced preceptors from National Library of Medicine staff
- Potential to compete for a second-year fellowship at a health sciences library in the United States
The Fellowship offers:
- A stipend equivalent to a U.S. Civil Service salary at the GS-9 level ($52,146 in 2014)
- Additional financial support for the purchase of health insurance
- Some relocation funding
The National Library of Medicine (NLM) Drug Information Portal is a free web resource that provides an informative, user–friendly gateway to current drug information for over 53,000 substances. The Portal links to sources from the NLM, the National Institutes of Health (NIH), and other government agencies such as the U.S. FDA. Current information regarding consumer health, clinical trials, AIDS–related drug information, MeSH pharmacological actions, PubMed biomedical literature, and physical properties and structure is easily retrieved by searching a drug name. A varied selection of focused topics in medicine and drug–related information is also available from displayed subject headings.
The Drug Portal retrieves by the generic or trade name of a drug or its category of usage. Records provide a description of how the drug is used, its chemical structure and nomenclature, and include up to 20 Resource Locators which link to more information in other selected resources. Recent additions to these Locators include clinical experience with drugs in PubMed Health, substances reviewed in NLM’s LiverTox, information from the Dietary Supplement Label Database, and drug images in the Pillbox database. Data in the Drug Information Portal is updated daily, and is also available on mobile devices. More information is available from the Drug Information Portal Fact Sheet.