Archive for the ‘NCBI’ Category
The full RefSeq release 67 is now available on the NCBI FTP site with over 61 million records describing 45,166,402 proteins, 8,163,775 RNAs, and sequences from 41,913 different NCBI TaxIDs.
More details about the RefSeq release 67 are included in the release statistics and release notes. In addition, reports indicating the accessions included in the release and the files installed are available.
* News story
* RefSeq release 67 on FTP
* Release statistics
* Release notes
* Accessions included report
* Files installed report
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NCBI Discovery Workshops, consisting of four 2.5-hour hands-on training sessions emphasizing NCBI resources such as BLAST and Nucleotide, will be presented by NCBI staff at the University of California, Davis, on September 15-16, and at the University of California, Berkeley, on September 17-18:
- Session 1: Navigating NCBI Molecular Data Through the Integrated Entrez System. 9 am – 11:30 am, 9/15 (UC Davis) & 9/17 (UC Berkeley)
- Session 2: NCBI Genomes, Assemblies and Annotation Products: Microbes to Human. 1 pm – 3:30 pm, 9/15 (UC Davis) & 9/17 (UC Berkeley)
- Session 3: Advanced NCBI BLAST. 9 am – 11:30 am, 9/16 (UC Davis) & 9/18 (UC Berkeley)
- Session 4: Gene Expression Resources at NCBI. 1 pm – 3:30 pm, 9/16 (UC Davis) & 9/18 (UC Berkeley)
For more information or to register:
A collaborative project between the National Library of Medicine’s National Center for Biotechnology Information (NCBI) and several other federal and state partners, to reduce the time and improve the accuracy of detecting foodborne pathogens by using whole genome sequencing (WGS) techniques, received the HHSinnovates award on July 21, 2014. The HHSinnovates program was initiated in 2010 to recognize new ideas and solutions developed by HHS employees and their collaborators. Six finalist teams were recognized at the awards ceremony. The WGS Food Safety Project, which also involved the Centers for Disease Control and Prevention (CDC), the Food and Drug Administration (FDA), the US Department of Agriculture (USDA), and state public health laboratories, was one of three projects to be honored as “Secretary’s Picks” by HHS Secretary Sylvia Mathews Burwell. The award went to the specific individuals leading the project in the various agencies; in the case of NCBI, Senior Scientist William Klimke, PhD, was honored for his work in heading NCBI’s part of the project.
WGS provides greater specificity than other techniques, such as the commonly used pulsed-field gel electrophoresis (PFGE), in identifying the DNA fingerprint of bacteria. It also can more rapidly determine whether isolates are related to a foodborne disease outbreak. The demonstration project involves real-time sequencing of Listeria monocytogenes isolates from human DNA as well as the food supply chain. In the project, the whole genomes of isolates are sequenced and the sequencing data are sent to NCBI, which performs assembly, annotation and analysis, and then sends results back to CDC, FDA, USDA and the labs. Collaborative projects using WGS for other pathogens related to food safety are also underway.
Attention health science librarians in the United States who wish to initiate and/or extend bioinformatics services at your institution! The National Center for Biotechnology Information (NCBI) and the NLM Training Center (NTC) will be offering “A Librarian’s Guide to NCBI” course in 2015. Participants who complete the class will be eligible for Medical Library Association (MLA) Continuing Education credits. The course is free, but travel costs are at the expense of the participant.
There are two parts to the course, and applicants must take both parts:
- Part 1: “Fundamentals in Bioinformatics and Searching” is a six-week, online (asynchronous) pre-course.
- Part 2: A five-day in-person course offered on-site at the National Library of Medicine in Bethesda, Maryland.
- Monday, September 29, 2014 – Watch for a detailed announcement about the course and application process in the NLM Technical Bulletin.
- Monday, November 17, 2014 – Application deadline.
- Monday, December 15, 2014 – Acceptance notifications e-mailed.
- Monday, January 12, 2015 – “Fundamentals in Bioinformatics and Searching” pre-course begins.
- Monday, March 9, 2015 – “A Librarian’s Guide to NCBI” five-day in-person class begins at NLM.
Mark your calendars for this training opportunity!
Dr. Harold Varmus’ memoir, The Art and Politics of Science, chronicles his path from a graduate student in English literature at Harvard to co-recipient of the Nobel Prize for cellular origin of retroviral oncogenes, to director of the National Institutes of Health, to President and CEO of Memorial Sloan-Kettering Cancer Center. The memoir is now freely available on the NCBI Bookshelf:
The Art and Politics of Science, by Dr. Harold Varmus. There are sections on PubMed: Virtues and Limitations and journal publishing from Chapter 15, Science Publishing and Science Libraries in the Internet Age.
NCBI has just released Entrez Direct, a new software suite that allows you to use the UNIX command line to directly access NCBI’s data servers, as well as parse and format data to create customized data files. The latest NCBI News story discusses Entrez Direct and gives several examples of how the programs may be used, as well as links to the suite on FTP and documentation. Entrez Direct is available as a simple FTP download and has extensive documentation on the NCBI web site.