Archive for the ‘Informatics’ Category
Health science librarians in the United States are invited to participate in the next offering of the bioinformatics training course, A Librarian’s Guide to NCBI, sponsored by the National Library of Medicine (NLM), the National Center for Biotechnology Information (NCBI), and the National Network of Libraries of Medicine, NLM Training Center (NTC). The course provides knowledge and skills for librarians interested in helping patrons use online molecular databases and tools from the NCBI. Prior knowledge of molecular biology and genetics is not required. Participating in the Librarian’s Guide course will improve your ability to initiate or extend bioinformatics services at your institution. Instructors will be NCBI staff and Diane Rein, Ph.D., MLS, Bioinformatics and Molecular Biology Liaison from the Health Science Library, University at Buffalo. There is no charge for the classes. Travel and lodging costs for the in-person class are at the expense of the participant.
There are two parts to A Librarian’s Guide to NCBI, listed below. Applicants must complete both parts. Participants must complete the pre-course with full CE credit (Part 1) in order to advance to attend the 5-day in-person course (Part 2). Part 1: Fundamentals in Bioinformatics and Searching is an online (asynchronous) course, January 12-February 13, 2015, and Part 2 is a 5-day in-person course offered on-site at the National Library of Medicine in Bethesda, MD, March 9-13, 2015. Students successfully completing the Fundamentals course (Part 1) will earn 18 MLA CE credits. Those successfully completing the 5-day in-person class (Part 2) will earn 36 additional MLA CE credits.
Applications are open to health science librarians in the United States. Applicants will be accepted both from libraries currently providing bioinformatics services as well as from those desiring to implement services. Enrollment is limited to 25 participants. The application deadline is November 17, 2014, and acceptance notification will be on or about December 15, 2014. Visit the A Librarian’s Guide to NCBI course page for additional information.
NCBI Discovery Workshops, consisting of four 2.5-hour hands-on training sessions emphasizing NCBI resources such as BLAST and Nucleotide, will be presented by NCBI staff at the University of California, Davis, on September 15-16, and at the University of California, Berkeley, on September 17-18:
- Session 1: Navigating NCBI Molecular Data Through the Integrated Entrez System. 9 am – 11:30 am, 9/15 (UC Davis) & 9/17 (UC Berkeley)
- Session 2: NCBI Genomes, Assemblies and Annotation Products: Microbes to Human. 1 pm – 3:30 pm, 9/15 (UC Davis) & 9/17 (UC Berkeley)
- Session 3: Advanced NCBI BLAST. 9 am – 11:30 am, 9/16 (UC Davis) & 9/18 (UC Berkeley)
- Session 4: Gene Expression Resources at NCBI. 1 pm – 3:30 pm, 9/16 (UC Davis) & 9/18 (UC Berkeley)
For more information or to register:
A collaborative project between the National Library of Medicine’s National Center for Biotechnology Information (NCBI) and several other federal and state partners, to reduce the time and improve the accuracy of detecting foodborne pathogens by using whole genome sequencing (WGS) techniques, received the HHSinnovates award on July 21, 2014. The HHSinnovates program was initiated in 2010 to recognize new ideas and solutions developed by HHS employees and their collaborators. Six finalist teams were recognized at the awards ceremony. The WGS Food Safety Project, which also involved the Centers for Disease Control and Prevention (CDC), the Food and Drug Administration (FDA), the US Department of Agriculture (USDA), and state public health laboratories, was one of three projects to be honored as “Secretary’s Picks” by HHS Secretary Sylvia Mathews Burwell. The award went to the specific individuals leading the project in the various agencies; in the case of NCBI, Senior Scientist William Klimke, PhD, was honored for his work in heading NCBI’s part of the project.
WGS provides greater specificity than other techniques, such as the commonly used pulsed-field gel electrophoresis (PFGE), in identifying the DNA fingerprint of bacteria. It also can more rapidly determine whether isolates are related to a foodborne disease outbreak. The demonstration project involves real-time sequencing of Listeria monocytogenes isolates from human DNA as well as the food supply chain. In the project, the whole genomes of isolates are sequenced and the sequencing data are sent to NCBI, which performs assembly, annotation and analysis, and then sends results back to CDC, FDA, USDA and the labs. Collaborative projects using WGS for other pathogens related to food safety are also underway.
The National Library of Medicine has announced that Georgia Regents University (GRU) will serve as the host organization for the NLM-sponsored biomedical informatics course. The NLM Biomedical Informatics Course, now entering its 22nd year, offers participants a week-long immersive experience in biomedical informatics taught by experts in the field. The course was previously held at the Marine Biological Laboratory (MBL) in Woods Hole, MA, with Cathy Norton, MLS, as the MBL principal investigator. NLM plans to take the skills shaped over the past two decades at MBL to its new colleagues at GRU. The first course organized at Georgia Regents University will be held September 14-20, 2014, followed by an additional session April 12-18, 2015. The course will be held at a conference center at the Brasstown Resort in Young Harris, GA, at no cost to participants.
Application to the course is open to anyone, but space is limited. Preference will be given to American applicants who demonstrate, through a brief application letter, that they have the significant need for an understanding of the informatics solutions that are available to address their biomedical research, practice and education challenges and that, through their official position, they are significant “change agents” who can influence the adoption of best practices in their own environment and expand the influence of the course to others through teaching or by example. The application deadline is July 7.
The course, co-directed by James J. Cimino, MD, Chief, Laboratory for Informatics Development at the National Library of Medicine and the NIH Clinical Center, and NLM Director Donald Lindberg, MD, will guide participants through topics including biomedical informatics methods, clinical informatics, big data and imaging, genomics, consumer health informatics, mathematical modeling, and telemedicine and telehealth. The co-principal investigators from GRU are Brenda L. Seago, MLS, MA, PhD, Professor and Director of Libraries, and Kathy J. Davies, MLS, Chair, Research and Education Services, Robert B. Greenblatt, MD Library.
NCBI has just released Entrez Direct, a new software suite that allows you to use the UNIX command line to directly access NCBI’s data servers, as well as parse and format data to create customized data files. The latest NCBI News story discusses Entrez Direct and gives several examples of how the programs may be used, as well as links to the suite on FTP and documentation. Entrez Direct is available as a simple FTP download and has extensive documentation on the NCBI web site.
The Coalition for Networked Information (CNI), the Association of Research Libraries (ARL), and EDUCAUSE have announced that Donald A.B. Lindberg, Director of the National Library of Medicine, has been named the 2014 recipient of the Paul Evan Peters Award. The award recognizes notable, lasting achievements in the creation and innovative use of network-based information resources and services that advance scholarship and intellectual productivity. Named for CNI’s founding director, the award honors the memory and accomplishments of Paul Evan Peters (1947–1996), a visionary and a coalition builder in higher education and the world of scholarly communication, who led CNI from its founding in 1990. The award will be presented during the CNI membership meeting in St. Louis, MO, to be held March 31–April 1, 2014, where Dr. Lindberg will deliver the Paul Evan Peters Memorial Lecture. The talk will be recorded and made available on CNI’s YouTube and Vimeo channels after the meeting concludes.
Dr. Lindberg’s interest in the potential intersection between information technology and the biological sciences stretches back to the early days of his career. He joined the pathology faculty at the University of Missouri in 1960, where he developed the first automated lab system and an automated patient history acquisition system. He implemented an automated statewide system for interpreting electrocardiograms, as well as other medical applications for the computer. Around this time, he also began publishing articles in a field that would come to be known as medical informatics, including The Computer and Medical Care, which appeared in 1968.
Dr. Lindberg has worked as a scientist for over 50 years, becoming widely recognized as an innovator in applying computer technology to health care, medical diagnosis, artificial intelligence, and educational programs. In 1984 he was appointed director of the National Library of Medicine (NLM), the world’s largest biomedical library, a post that he still holds. As NLM’s Director, Dr. Lindberg convinced the United States Congress that the Library was an essential information conduit, facilitating the decision-making process of scientists and pharmaceutical companies, and, ultimately, benefiting patients and the general public, thereby securing the organization’s robust future. He has spearheaded countless transformative programs in medical informatics, including the Unified Medical Language System, making it possible to link health information, medical terms, drug names and billing codes across different computer systems; the Visible Human Project, a digital image library of complete, anatomically detailed, three-dimensional representations of the normal male and female human bodies; the production and implementation of ClinicalTrials.gov, a registry and results database of publicly and privately supported clinical studies of human participants conducted around the world; and, the establishment of the National Center for Biotechnology Information, a national resource for molecular biology information and genetic processes that control health and disease. Today, NLM has a budget of $327 million, more than 800 employees, and digital information services that are used billions of times a year by millions of scientists, health professionals, and members of the public.
Dr. Lindberg is a member of the Institute of Medicine of the National Academy of Sciences, and has received numerous honors and awards, including the prestigious Morris F. Collen, MD, Award of Excellence of the American College of Medical Informatics, and the Surgeon General’s Medallion of the US Public Health Service. He received his medical degree from the College of Physicians and Surgeons, Columbia University, and an undergraduate degree from Amherst College. A four-member committee selected Dr. Lindberg for the award: the late Ann J. Wolpert, director of libraries at the Massachusetts Institute of Technology; George O. Strawn, director of the Federal Networking and Information Technology Research and Development (NITRD) National Coordination Office (NCO); Sally Jackson, professor of communication at the University of Illinois at Urbana-Champaign; and Joan Lippincott, associate executive director of the Coalition for Networked Information.
The NCBI, in partnership with the National Library of Medicine Training Center (NTC), will offer the Librarian’s Guide to NCBI course on the NIH campus in April 2014. This will be the second presentation of the course; it was previously offered in the spring of 2013. After the course, lecture slides and hands-on practical exercises will be posted on the education area of the NCBI FTP site and video tutorials of the course lectures will be available on the NCBI YouTube channel. Materials from the 2013 course are currently available.
A Librarian’s Guide is an intense five-day exploration of modern molecular biology, genetic, and other biomedical data as represented at the NCBI. The course explains how and why these data are generated, their importance in modern biomedical research, and how to access them through the NCBI Web site. It is intended for medical librarians in the United States who currently are offering bioinformatics education and support services to their patrons or are planning to offer such services in the future. More information is available in the newest NCBI Insights blog post.
All applicants for A Librarian’s Guide must have successfully completed the asynchronous online Fundamentals of Bioinformatics and Searching class, which is a six-week introduction to molecular biology and bioinformatics taught by Diane Rein, Ph.D., MLS, and offered through the NTC. The Fundamentals course is open to any medical librarian in the United States interested in an introduction to bioinformatics and NCBI resources. A winter 2014 Fundamentals class, which runs from February 10 – March 21, 2014, is open for applications. Only people who have successfully completed the Fundamentals class may apply to A Librarian’s Guide to NCBI. The application process for eligible Fundamentals candidates will be announced in February 2014.
Health science librarians are invited to participate in an online bioinformatics training course, Fundamentals of Bioinformatics and Searching, sponsored by the National Library of Medicine (NLM), the National Center for Biotechnology Information (NCBI), and the National Network of Libraries of Medicine, NLM Training Center (NTC). The course provides basic knowledge and skills for librarians interested in helping patrons use online molecular databases and tools from the NCBI. Attending this course will improve your ability to initiate or extend bioinformatics services at your institution. Prior knowledge of molecular biology and genetics is not required.
The major goal of this course is to provide an introduction to bioinformatics theory and practice in support of developing and implementing library-based bioinformatics products and services. This material is essential for decision-making and implementation of these programs, particularly instructional and reference services. The course encompasses visualizing bioinformatics end-user practice, places a strong emphasis on hands-on acquisition of NCBI search competencies, and a working molecular biology vocabulary, through self-paced hands-on exercises.
This course is offered online (asynchronous) from October 21 – December 2, 2013. The course format includes video lectures, readings, a molecular vocabulary exercise, an NCBI discovery exercise, and other hands-on exercises. The instructor is Diane Rein, Ph.D., MLS, Bioinformatics and Molecular Biology Liaison from the Health Science Library, University at Buffalo. Due to limited enrollment, interested participants are required to complete an application form. The deadline for completing the application is September 9, 2013; participants will be notified of acceptance on September 23, 2013.
The course is offered at no cost to participants. Participants who complete all assignments and the course evaluation by the due dates within the course will receive 15 hours of MLA CE credit. No partial CE credit is granted. This course is a prerequisite for the face-to-face workshop, Librarian’s Guide to NCBI. Participants who complete the required coursework and earn full continuing education credit will be eligible to apply to attend the five-day Librarian’s Guide that will be offered in April of 2014. Questions about the online course may be directed to the course organizers.
The National Library of Medicine’s (NLM) Medical Text Indexer is being used as one of the baselines for the international BioASQ challenge. The Medical Text Indexer (MTI), a system for producing indexing recommendations, assists in the indexing process at NLM. The BioASQ challenge is a series of challenges on biomedical semantic indexing and question answering, with the aim of advancing the state of the art accessibility for researchers and clinicians to biomedical text. The MTI indexing results are providing one of the baselines used in the “Large-scale online biomedical semantic indexing” part of the challenge, which is designed to parallel the human indexing currently being done at NLM. Alan R. Aronson, PhD, Principal Investigator for the MTI project, also will be delivering an invited talk on Indexing The Biomedical Literature In A Time Of Increased Demand And Limited Resources at the BioASQ Workshop in September. Dr. Aronson is a Principal Investigator at the Lister Hill National Center for Biomedical Communications, an Intramural Research Division of the National Library of Medicine.
The National Library of Medicine (NLM) has announced its next initiative as part of its ongoing partnership with the National Endowment for the Humanities (NEH). Working with NEH’s Office of Digital Humanities, the National Science Foundation, and Virginia Polytechnic Institute and State University (Virginia Tech), the NLM will be a part of An Epidemiology of Information: New Methods for Interpreting Disease and Data, an interdisciplinary symposium exploring new methods for large-scale data analysis of epidemic disease.
Scheduled to take place at the Virginia Tech Research Center in Arlington, VA, on October 17, 2013, from 8:30 AM to 5:00 PM, “An Epidemiology of Information” will be a unique public forum through which policy makers, public health experts, and scholars can address pressing questions about how new methods of analyzing large-scale datasets can inform research and policy approaches to epidemic disease. Panelists will consider what these new methods suggest for contemporary infodemiology and epidemic intelligence, as well as the implications of data mining as a disease surveillance mechanism, and how new forms of reporting and public health surveillance affect public health policy. The symposium will also explore how these new methods can inform research on the 1918 influenza pandemic, and help to answer lingering questions about the spread of the disease, its pathogenicity, the unusual mortality rates, or the effectiveness of public health responses.
Featured speakers will include Dr. Jeffery Taubenberger, Chief, Viral Pathogenesis and Evolution Section, National Institute of Allergy and Infectious Diseases (NIAID), and Dr. David Morens, Senior Advisor to the Director, NIAID, whose research in data analysis and historical epidemiology has influenced the approaches being adopted and adapted by digital humanities scholars working in the history of medicine. “An Epidemiology of Information” is made possible in part from support received by Virginia Tech through the international Digging into Data Challenge competition sponsored by NEH. Funding for Virginia Tech’s Canadian partner, the Center for E-Health Initiatives of the University of Toronto, comes from the Social Science and Humanities Research Council of Canada. The symposium is free and open to the public, but registration is required.